PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G45710.1
Common NameAT-HSFA4C, HSF20, HSFA4C, MRA19.11, RHA1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 345aa    MW: 39647.8 Da    PI: 5.6822
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G45710.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind105.64.1e-33141052102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k+ye+++d++ ++++ wsen++sf+v+++ ef++++Lp++Fkh+nf+SF+RQLn+YgF+kv+ e+         weF ++ F +g+  l+++i+
   AT5G45710.1  14 FLTKTYEMVDDSSSDSVVAWSENNKSFIVKNPAEFSRDLLPRFFKHKNFSSFIRQLNTYGFRKVDPEK---------WEFLNDDFVRGRPYLMKNIH 101
                   9****************************************************************999.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   r+k 
   AT5G45710.1 102 RRKP 105
                   *985 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467852.18E-339103IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004153.6E-5710103IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.101.2E-3511103IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004471.5E-2914103IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000567.0E-191437IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000567.0E-195264IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043405377IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000567.0E-196577IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0009733Biological Processresponse to auxin
GO:0009958Biological Processpositive gravitropism
GO:0048527Biological Processlateral root development
GO:0048530Biological Processfruit morphogenesis
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001016developmental stageL mature pollen stage
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 345 aa     Download sequence    Send to blast
MDENNGGSSS LPPFLTKTYE MVDDSSSDSV VAWSENNKSF IVKNPAEFSR DLLPRFFKHK  60
NFSSFIRQLN TYGFRKVDPE KWEFLNDDFV RGRPYLMKNI HRRKPVHSHS LVNLQAQNPL  120
TESERRSMED QIERLKNEKE GLLAELQNQE QERKEFELQV TTLKDRLQHM EQHQKSIVAY  180
VSQVLGKPGL SLNLENHERR KRRFQENSLP PSSSHIEQVE KLESSLTFWE NLVSESCEKS  240
GLQSSSMDHD AAESSLSIGD TRPKSSKIDM NSEPPVTVTA PAPKTGVNDD FWEQCLTENP  300
GSTEQQEVQS ERRDVGNDNN GNKIGNQRTY WWNSGNVNNI TEKAS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5v_D2e-22710322129Heat shock factor protein 1
5d5v_B2e-22710322129Heat shock factor protein 1
5d5u_B2e-22710322129Heat shock factor protein 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.439160.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible248936_at0.0
Expression AtlasAT5G45710-
AtGenExpressAT5G45710-
ATTED-IIAT5G45710-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings and at lower levels in leaves. {ECO:0000269|PubMed:18381353}.
Functional Description ? help Back to Top
Source Description
TAIRmember of Heat Stress Transcription Factor (Hsf) family
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). May be involved in general response to auxin. {ECO:0000269|PubMed:18381353}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G45710.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat and cold stresses and the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D, auxin analog). {ECO:0000269|PubMed:18381353}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDauxin, ethylene
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Plants display minimal right-handed slanting in roots, reduced gravitropic response, reduced number of lateral roots, reduced size of shoot and root in the seedlings and increased resistance to 2,4-D. {ECO:0000269|PubMed:18381353}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G45710
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2290580.0AK229058.1 Arabidopsis thaliana mRNA for heat shock transcription factor, complete cds, clone: RAFL16-34-M14.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_199383.10.0heat stress transcription factor A-4c
SwissprotQ9FK720.0HFA4C_ARATH; Heat stress transcription factor A-4c
TrEMBLD7MTC40.0D7MTC4_ARALL; AT-HSFA4C
STRINGAT5G45710.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM28532868
Representative plantOGRP52351020
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nover L, et al.
    Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
    Cell Stress Chaperones, 2001. 6(3): p. 177-89
    [PMID:11599559]
  3. Piconese S,Tronelli G,Pippia P,Migliaccio F
    Chiral and non-chiral nutations in Arabidopsis roots grown on the random positioning machine.
    J. Exp. Bot., 2003. 54(389): p. 1909-18
    [PMID:12869523]
  4. Fortunati A,Piconese S,Tassone P,Ferrari S,Migliaccio F
    A new mutant of Arabidopsis disturbed in its roots, right-handed slanting, and gravitropism defines a gene that encodes a heat-shock factor.
    J. Exp. Bot., 2008. 59(6): p. 1363-74
    [PMID:18381353]
  5. Guo J, et al.
    Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis.
    J Genet Genomics, 2008. 35(2): p. 105-18
    [PMID:18407058]
  6. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  7. Fortunati A,Piconese S,Tassone P,Ferrari S,Migliaccio F
    Rha1, a new mutant of Arabidopsis disturbed in root slanting, gravitropism and auxin physiology.
    Plant Signal Behav, 2008. 3(11): p. 989-90
    [PMID:19704429]